Only if they win a civil war. The government of Spain is not having any of this shit. That is why this is an "informal" vote because the government did not give them a permission to vote on this.
(The fact that Catalonia is the rich part of Spain that is actually doing well is reason enough for the government not to want them secede.)
EDIT: Turns out that the article isn't quite true. The title at least is
extremely misleading.
Like Paragon's post says:
Vice President Joana Ortega said that more than two million people had taken part in the poll and that with almost all votes counted, 80.72% had backed independence.
Two million out of 5.4 million eligible voters. And because anyone over the age 16 was allowed to vote in this "informal poll" the amount of potential voters in the region was 6.3 million people and they only managed to get a third of them to vote for independence.
It is possible that the most of the people who want the independence came to vote and they are still a minority in the region.
Opinion polls suggest that as many as 80% of Catalans want an official referendum on the issue of Catalonia's status, with about 50% in favour of full independence.
Oh, and even from those two million less than a million want independence.