What about God and the Serpent in the Biblical Book of Genesis, as the Designated Hero and Villain, respectively?
God creates Adam and Eve, but creates them without the knowledge of right and wrong. He then places a tree in their garden and commands them to never eat from it, or they'll die. Which is somehow supposed to make sense to a pair of people who can neither conceptualize death nor obedience.
Enter the Serpent, who tells them that God was lying and they won't die if they eat from the tree, and instead they'll gain the knowledge of right and wrong. So, Adam and Eve eat from the tree, don't die, and are only now able to understand that what they did was wrong once they'd already done it.
God gets mad at them breaking an order that they could have only followed once they'd already broken it, and kicks them out of the garden and punishes them for all eternity.
The Serpent is always called the "trickster" in this story, but really, what did it ever say that was untrue? Is this implying that humanity would have been better off as ignorant robots without a conscience?